Cheap flights from Buffalo Niagara to Des Moines

Compare Buffalo Niagara to Des Moines flight deals

Find the cheapest month or even day of the year to fly to Des Moines

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Flight deals from Buffalo Niagara to Des Moines

Looking for a cheap last-minute deal or the best return flight from Buffalo Niagara to Des Moines? Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Buffalo Niagara to Des Moines

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Buffalo Niagara to Des Moines flights are currently cheapest in January.

Buffalo Niagara to Des Moines: Alternative routes

Compare routes from Buffalo Niagara to Des Moines below. You may find an airport to fly into that's cheaper, faster, or easier than Des Moines.

Buffalo to Des Moines: Flight information

The things to know before you go.
Cheapest flight found$301
Cheapest month to flyJanuary

Finding cheap flights from Buffalo Niagara to Des Moines: Frequently asked questions

The best price we found for a return flight from Buffalo Niagara to Des Moines is $378. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Buffalo Niagara to Des Moines. But we found flights with one or more stops from $378.
As of December 2025, there are no flights flying from Buffalo Niagara to Des Moines.
The cheapest month to fly from Buffalo Niagara to Des Moines is usually January.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Buffalo Niagara Airport to Des Moines Airport on Saturday, 10 January 2026.
No airlines currently offer direct flights between Buffalo Niagara Airport and Des Moines Airport. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Des Moines but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Des Moines is around 40 days in advance, so don’t leave your flight to the last minute.
Currently, United offers the cheapest flight tickets to Des Moines.

Travelling from Buffalo Niagara International Airport (BUF) to Des Moines International Airport (DSM): what you need to know

  • Arriving two hours before an international flight and one hour ahead of a domestic departure are golden rules for hassle-free flying. Make sure you're at the airport on time to board your BUF to DSM flight.

  • During popular months like August, it's a good idea to get to the airport well in advance. Arrive two hours before a domestic departure and four hours ahead of international flights whenever you're flying during a high season in general.

  • Think about adding a stopover when booking your ticket from Buffalo Niagara International Airport to Des Moines International Airport. Just uncheck 'Direct flights only' to break up your trip, or maybe even explore a new city along the way. Here are some options between BUF and DSM:

    • Detroit Metropolitan Wayne County Airport

    • O'Hare International Airport

    • Nashville International Airport

How to find the cheapest flights from Buffalo Niagara International Airport (BUF) to Des Moines International Airport (DSM)

  • $301 is currently the lowest price for a one-way Buffalo Niagara International Airport to Des Moines International Airport flight. A return flight starts at $378. These prices may change depending on availability.

  • It's usually best to book in advance if you want to get cheap tickets from BUF to DSM. That's because flight prices are based on demand, which tends to increase closer to departure.

  • If you can be flexible with your travel plans, use the 'Whole month' search function. It'll show you the lowest price across every month when looking for your flight from Buffalo Niagara International Airport to Des Moines International Airport.

  • Getting your hands on cheap flights from BUF to DSM is a piece of cake with Price Alerts. All you need to do is create one of these automatic alerts and we'll get in touch when a new deal comes up.

  • Pick your ideal arrival and departure times, airlines and number of stops with the filters. Or sort your results by 'Cheapest' to find the best deals on flights from Buffalo Niagara International Airport to Des Moines International Airport.

Handy information about Buffalo Niagara International Airport (BUF)

  • The address for BUF is Genesee Street.

  • Of all flights leaving Buffalo Niagara International Airport, 75.46% land on schedule at their destination.

  • Buffalo Niagara International Airport is around 18 kilometres from central Buffalo. If you're catching a cab, ride-sharing or driving from the centre, it'll take 20 minutes or so to get there, depending on the traffic.

  • The trip on public transport usually takes 1 hour 15 minutes.

  • Get your travels off to a relaxed start by staying near BUF. Whether you're boarding an early flight from Buffalo Niagara International Airport to Des Moines International Airport or want to avoid feeling rushed, these hotels are ideal:

Arriving at Des Moines International Airport (DSM)

Getting from Des Moines International Airport (DSM) to central Des Moines

  • You'll find DSM at 5800 Fleur Drive, Suite 201.

  • From Des Moines International Airport, Des Moines is approximately 10 kilometres away. It takes around 15 minutes to drive to the centre.

  • If you're travelling by public transport, expect a journey of about 45 minutes.

When to fly to Des Moines International Airport (DSM)

  • July is the busiest month for flights from Buffalo Niagara International Airport to Des Moines International Airport. To skip the crowds, visit Des Moines in April.

  • The warmest month in Des Moines is July, with the temperature ranging between 15ºC (59ºF) and 31ºC (88ºF). Lock in your flights from Buffalo Niagara International Airport to Des Moines International Airport in this month if this is the kind of weather you like.

  • For cooler conditions, look for a cheap ticket from BUF to DSM in January. Temperatures average between -13ºC (9ºF) and 2ºC (36ºF) then.

Explore more of United States

  • Des Moines is always a good idea, but there are so many other parts of United States just waiting to be explored. About 499 kilometres east of Des Moines, a visit to Chicago will keep you on the move. Start with attractions like Millennium Park, Art Institute of Chicago and LandShark Beer Garden at Navy Pier.

  • If you're eager to discover another well-known destination in United States, head for Milwaukee, roughly 499 kilometres east of Des Moines. Miller Park, Pabst Mansion and Milwaukee Public Museum are the start of reasons to visit.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.