Cheap flights from Philadelphia to Knoxville

Compare Philadelphia to Knoxville flight deals

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Flight deals from Philadelphia to Knoxville Airport

Looking for a cheap last-minute deal or the best return flight from Philadelphia to Knoxville Airport? If you want to travel next month, return fares start from $394. Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Philadelphia to Knoxville

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Philadelphia to Knoxville flights are currently cheapest in May.

Direct flights from Philadelphia to Knoxville

Philadelphia to Knoxville: Alternative routes

Compare routes from Philadelphia to Knoxville below. You may find an airport to fly into that's cheaper, faster, or easier than Knoxville.

Philadelphia to Knoxville: Flight information

The things to know before you go.
Cheapest flight found$62
Cheapest month to flyMay
Average flight time2 hrs, 11 mins
Most popular airlineAmerican Airlines
Average flights per week192

Finding cheap flights from Philadelphia to Knoxville: Frequently asked questions

The best price we found for a return flight from Philadelphia to Knoxville is $119. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
2 hours and 11 minutes is the average flight time from Philadelphia to Knoxville.
American Airlines, Piedmont Airlines and Qatar Airways fly direct from Philadelphia to Knoxville.
As of March 2026, there are 96 flights per week flying from Philadelphia to Knoxville.
The cheapest month to fly from Philadelphia to Knoxville is usually May.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Philadelphia to Knoxville Airport on Thursday, 21 May 2026.
Yes – the average flight time is 2 hours and 11 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Knoxville but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Knoxville is around 40 days in advance, so don’t leave your flight to the last minute.
The cheapest airline that flies to Knoxville is Allegiant Air .

Travelling from Philadelphia to McGhee Tyson Airport (TYS): What you need to know

  • Start your trip planning by checking out where you'll catch your flight from Philadelphia to McGhee Tyson Airport (TYS). Explore the options for taking off from Philadelphia International Airport (PHL) or Trenton-Mercer Airport (TTN), two of the city's main airports.

  • Jump on a direct Philadelphia to McGhee Tyson Airport flight and you'll be in the air for an average of 2 hours 5 minutes.

  • McGhee Tyson Airport is located in Knoxville. The city's timezone is UTC-4, which is the same as Philadelphia.

  • With 21 direct flights a week between the two airports, Philadelphia International Airport (PHL) to McGhee Tyson Airport (TYS) is the most popular route. American Airlines operates the earliest flight at 8:14am. If you're eager to get more out of your day before taking off, the last flight from PHL to TYS is with American Airlines at 6:56pm.

  • Your flight from Philadelphia to TYS won't wait if you're late, so get to the airport with time to spare. Arrive up to one hour in advance for domestic flights and two hours ahead when you're flying internationally.

  • Travelling during a peak time like school or public holidays? Expect longer queues at check-in and security. Give yourself extra leeway and arrive up to four hours before international flights and two hours ahead of domestic departures.

Airports in Philadelphia

Philadelphia International Airport (PHL)

  • You can take a direct flight from Philadelphia to McGhee Tyson Airport (TYS) leaving from Philadelphia International Airport (PHL).

  • American Airlines is a popular airline that offers direct flights from Philadelphia to McGhee Tyson Airport departing from PHL.

  • The majority of passengers choose to fly with American Airlines between PHL and TYS.

  • With a reliable 80.89% of services arriving as scheduled, American Airlines is the most punctual carrier operating on this route.

  • PHL is around 19 kilometres from central Philadelphia. If you're driving, ride-sharing or catching a cab from the centre, it'll take you 15 minutes or so to get there, depending on traffic conditions. If you're taking public transport, expect the travel time to be around 45 minutes.

  • Want a stress-free start to your break? Stay near Philadelphia International Airport. Whether you have an early flight from Philadelphia to McGhee Tyson Airport or just don't like being rushed, these hotels are the answer:

  • 78.93% of flights departing from Philadelphia International Airport reach their destination on schedule.

  • You'll find PHL at 8500 Essington Ave.

Trenton-Mercer Airport (TTN)

  • Using public transport, you can travel from central Philadelphia to TTN in about 1 hour 45 minutes. The airport is roughly 56 kilometres away, and making the trip by car takes approximately 40 minutes.

  • Start your holiday sooner with an extra night away from home. Before your Philadelphia to TYS flight, kick back in one of these hotels near Trenton-Mercer Airport:

  • Flights from Trenton-Mercer Airport have a proven record for punctuality, with 82.45% of them arriving within the expected time frame.

  • TTN is located at Scotch Road, Terminal Building.

About McGhee Tyson Airport (TYS)

  • If you're coming in on a late flight from Philadelphia to McGhee Tyson Airport, nothing tops the convenience of staying close to the terminal. Pick up your luggage at baggage claim and then be showered and snoozing not long after at one of these options near TYS:

  • Get on the fast track to adventure by picking up a McGhee Tyson Airport rental car. Grab a set of wheels from Budget, Alamo or Avis and experience the lesser-explored corners of Knoxville and beyond.

  • Get the best deal by reserving your ride around three weeks ahead of your Philadelphia to McGhee Tyson Airport flight.

  • TYS is located at 2055 Alcoa Highway.

How to find the cheapest flights from Philadelphia to McGhee Tyson Airport (TYS)

  • The cheapest price we've found for a one-way ticket from Philadelphia to McGhee Tyson Airport is $62. For a return flight on this route, the best price is $119. Depending on the availability when you book, these fares can change.

  • Booking in advance is often the key to finding a cheap flight from Philadelphia to TYS. Prices tend to rise as demand increases, so the closer you get to departure, the more expensive your ticket may be.

  • The 'Whole month' tool shows you the cheapest Philadelphia to McGhee Tyson Airport tickets throughout the entire month. It's a great way to snap up a bargain if your travel dates are flexible.

  • There's no need to search every day to find out if prices have dropped when you set up a Price Alert. We'll let you know as soon as a better deal comes up on plane tickets from Philadelphia to TYS.

  • Chase down a great fare on a flight from Philadelphia to McGhee Tyson Airport with the help of the filters. Choose your ideal arrival and departure times, airlines and number of stops. You can also sort your results by 'Fastest,' 'Cheapest' or 'Best.'

The best time to fly from Philadelphia to McGhee Tyson Airport (TYS)

  • Think about the pace you're looking for when deciding your trip dates. February is the quietest month to go to Knoxville. July is when most people book flights from Philadelphia to McGhee Tyson Airport (TYS), which may be perfect if you enjoy travelling when it's busier.

  • The warmest month in Knoxville is July, with temperatures ranging between 17ºC (63ºF) and 32ºC (90ºF). Lock in your Philadelphia to TYS plane ticket then if that's your ideal forecast.

  • If you'd rather travel in cooler conditions, search for a cheap ticket from Philadelphia to McGhee Tyson Airport in January when temperatures are between -6ºC (21ºF) and 11ºC (52ºF).

More about Knoxville

Explore more of the United States

  • You've visited Knoxville, now it's time to discover more of the United States. Journey about 290 kilometres east to Charlotte to tick off its top sights. From Bechtler Museum of Modern Art to Discovery Place and NASCAR Hall of Fame, there's plenty to keep you on the go.

  • Around 257 kilometres west of Knoxville, Nashville is another essential stop in the United States. Experience this destination's highlights firsthand at Grand Ole Opry, Country Music Hall of Fame and Museum and The Johnny Cash Museum.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.