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Cheap flights from Manaus to Panama City

Compare Manaus to Panama City flight deals

Find the cheapest month or even day of the year to fly to Panama City

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Flight deals from Manaus to Panama City

Looking for a cheap last-minute deal or the best return flight from Manaus Airport to Panama City? If you want to travel next month, return fares start from $537. Find the lowest prices on one-way and return tickets right here.
Panama City.$243 per passenger.Departing Thu, 27 Aug.One-way flight with Avianca.Outbound indirect flight with Avianca, departs from Manaus on Thu, 27 Aug, arriving in Panama City Tocumen International.Price includes taxes and charges.From $243, select.
Panama City.$247 per passenger.Departing Thu, 8 Oct.One-way flight with Avianca.Outbound indirect flight with Avianca, departs from Manaus on Thu, 8 Oct, arriving in Panama City Tocumen International.Price includes taxes and charges.From $247, select.
Panama City.$248 per passenger.Departing Mon, 15 Jun.One-way flight with Avianca.Outbound indirect flight with Avianca, departs from Manaus on Mon, 15 Jun, arriving in Panama City Tocumen International.Price includes taxes and charges.From $248, select.
Panama City.$248 per passenger.Departing Thu, 14 Jan.One-way flight with Avianca.Outbound indirect flight with Avianca, departs from Manaus on Thu, 14 Jan, arriving in Panama City Tocumen International.Price includes taxes and charges.From $248, select.
Panama City.$248 per passenger.Departing Mon, 23 Nov.One-way flight with Avianca.Outbound indirect flight with Avianca, departs from Manaus on Mon, 23 Nov, arriving in Panama City Tocumen International.Price includes taxes and charges.From $248, select.
Panama City.$249 per passenger.Departing Mon, 3 May.One-way flight with Avianca.Outbound indirect flight with Avianca, departs from Manaus on Mon, 3 May, arriving in Panama City Tocumen International.Price includes taxes and charges.From $249, select.
Panama City.$249 per passenger.Departing Thu, 10 Sep.One-way flight with Avianca.Outbound indirect flight with Avianca, departs from Manaus on Thu, 10 Sep, arriving in Panama City Tocumen International.Price includes taxes and charges.From $249, select.
Panama City.$249 per passenger.Departing Mon, 8 Mar.One-way flight with GOL Linhas Aéreas.Outbound indirect flight with GOL Linhas Aéreas, departs from Manaus on Mon, 8 Mar, arriving in Panama City Tocumen International.Price includes taxes and charges.From $249, select.
Panama City.$249 per passenger.Departing Tue, 23 Feb.One-way flight with Avianca.Outbound indirect flight with Avianca, departs from Manaus on Tue, 23 Feb, arriving in Panama City Tocumen International.Price includes taxes and charges.From $249, select.
Panama City.$250 per passenger.Departing Mon, 7 Dec.One-way flight with Avianca.Outbound indirect flight with Avianca, departs from Manaus on Mon, 7 Dec, arriving in Panama City Tocumen International.Price includes taxes and charges.From $250, select.
Panama City.$250 per passenger.Departing Mon, 27 Jul.One-way flight with GOL Linhas Aéreas.Outbound indirect flight with GOL Linhas Aéreas, departs from Manaus on Mon, 27 Jul, arriving in Panama City Tocumen International.Price includes taxes and charges.From $250, select.
Panama City.$662 per passenger.Departing Mon, 22 Jun.One-way flight with Copa.Outbound direct flight with Copa departs from Manaus on Mon, 22 Jun, arriving in Panama City Tocumen International.Price includes taxes and charges.From $662, select.
Panama City.$726 per passenger.Departing Sat, 12 Dec.One-way flight with Copa.Outbound direct flight with Copa departs from Manaus on Sat, 12 Dec, arriving in Panama City Tocumen International.Price includes taxes and charges.From $726, select.
Panama City.$831 per passenger.Departing Sat, 29 Aug.One-way flight with Copa.Outbound direct flight with Copa departs from Manaus on Sat, 29 Aug, arriving in Panama City Tocumen International.Price includes taxes and charges.From $831, select.
Panama City.$831 per passenger.Departing Thu, 14 Jan.One-way flight with Copa.Outbound direct flight with Copa departs from Manaus on Thu, 14 Jan, arriving in Panama City Tocumen International.Price includes taxes and charges.From $831, select.
Panama City.$832 per passenger.Departing Tue, 23 Feb.One-way flight with Copa.Outbound direct flight with Copa departs from Manaus on Tue, 23 Feb, arriving in Panama City Tocumen International.Price includes taxes and charges.From $832, select.

Find the cheapest month to fly from Manaus to Panama City

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Manaus to Panama City flights are currently cheapest in August.
Jun
from $248
Jul
from $250
Aug
from $243
Sep
from $249
Oct
from $247
Nov
from $248
Dec
from $250
Jan
from $248
Feb
from $249
Mar
from $249
Apr
from $833
May
from $249

Direct flights from Manaus to Panama City

Alternative Manaus to Panama City routes

Looking for the cheapest, fastest or easiest route from Manaus to Panama City? You could fly into the following airports instead.

Panama City Paitilla

5km from central Panama City
Closest
from $1,209
Search flights

Balboa

5km from central Panama City
from $456
Search flights

Panama City Tocumen International

18km from central Panama City
Cheapest
from $243
Search flights

Manaus to Panama City: Flight information

The things to know before you go.
Cheapest flight found$243
Cheapest month to flyAugust
Average flight time3 hrs, 48 mins
Most popular airlineCopa
Average flights per week46

Finding cheap flights from Manaus to Panama City: Frequently asked questions

There are 3 airports in Panama City: Panama City Paitilla, Balboa and Panama City Tocumen International.
The best price we found for a return flight from Manaus to Panama City is $536. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
3 hours and 48 minutes is the average flight time from Manaus to Panama City.
Copa, GOL Linhas Aéreas and Azul Airlines fly direct from Manaus to Panama City.
As of June 2026, there are 44 flights per week flying from Manaus to Panama City.
The cheapest month to fly from Manaus to Panama City is usually July.
If you're flying from Manaus Airport, the cheapest airport near Panama City is Panama City Tocumen International – which is 17.9 km away from the centre of Panama City. We've found flights into this airport from $536.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Manaus Airport to Panama City on Tuesday, 28 July 2026.
Yes – the average flight time is 3 hours and 48 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Panama City but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Panama City is around 40 days in advance, so don’t leave your flight to the last minute.
In June, the average temperature is usually around 27°C. May is typically the warmest month in Panama City, when it usually averages around 29°C. You can expect the least rain in February. The coldest month is October, with temperatures averaging 25°C. The rainiest month is June.
Currently, GOL Linhas Aéreas and Copa offer the cheapest flight tickets to Panama City.

Flying from Manaus Eduardo Gomes International Airport (MAO) to Panama City: what you need to know

  • Approximately 3 hours 55 minutes is how long you'll be travelling on a direct flight from Manaus Eduardo Gomes International Airport to Panama City.

  • Panama City is one hour behind Manaus, where Manaus Eduardo Gomes International Airport is located. Panama City observes the UTC-5 timezone.

  • With seven weekly flights between the two airports, Manaus Eduardo Gomes International Airport (MAO) to Panama City Tocumen International Airport (PTY) is the busiest route. Board Copa Airlines's 03:35 flight to get your journey from MAO to PTY underway.

  • Allow plenty of time to make your MAO to Panama City flight. Generally, it's best to arrive at least two hours before international departures and an hour ahead for domestic flights.

  • You'll likely experience bigger queues during popular months such as January. Arriving up to four hours in advance for an international flight and two hours for domestic departures will help ensure a smooth travel experience.

  • Direct Manaus Eduardo Gomes International Airport to Panama City tickets are available for booking. Panama City Tocumen International Airport (PTY) is where you'll be landing.

  • Check out the deals with Copa Airlines. This carrier has direct flights from Manaus Eduardo Gomes International Airport to Panama City.

  • Stopovers offer the perfect opportunity to explore a new place or just have a break during your travels. When searching for a plane ticket from MAO to Panama City, deselect 'Direct flights only' to check out all potential stops. Bogota El Dorado International Airport (BOG) is one option.

  • The journey from central Manaus to MAO takes around 50 minutes by public transport. If you drive, ride-share or take a taxi, you'll cover the 48 kilometres in 25 minutes or so, depending on traffic.

  • Want a stress-free start to your trip? Stay near MAO. Whether you have an early flight from Manaus Eduardo Gomes International Airport to Panama City or just don't like being rushed, these hotels are worth a look:

  • Manaus Eduardo Gomes International Airport scores top marks for its on-time performance. 82% of flights that take off from MAO arrive at their destination without delay.

How to find the cheapest flights from Manaus Eduardo Gomes International Airport (MAO) to Panama City

  • The best price we've seen for a one-way Manaus Eduardo Gomes International Airport to Panama City flight is $243. The cheapest price for a return flight is $536. Keep in mind fares can change due to availability at the time of booking.

  • To snag cheap flights from MAO to Panama City, reserve your trip three months ahead of your planned departure.

  • The best month for finding cheap Manaus Eduardo Gomes International Airport to Panama City tickets is August. Use the 'Whole month' tool to compare prices, then choose the dates with the lowest fares.

  • Save time searching for cheap flights from MAO to Panama City by setting up a Price Alert. You'll get an email or notification on the app when a lower fare becomes available.

  • Tailor your flights with filters. Pick your preferred arrival and departure times, airlines and total journey duration. You can also sort your results by 'Best,' 'Fastest' or 'Cheapest' flights from Manaus Eduardo Gomes International Airport to Panama City.

Airports in Panama City

Panama City Tocumen International Airport (PTY)

  • The distance from Panama City Tocumen International Airport (PTY) to central Panama City is roughly 24 kilometres. It takes around 35 minutes to get to the centre driving.

  • When travelling by public transport, expect a journey time of around 50 minutes.

  • The last thing you want is a lengthy journey to your hotel if you're getting in late on a flight from Manaus Eduardo Gomes International Airport to Panama City. Reserve one of these accommodation options near PTY instead:

  • To lock in the lowest price, reserve your ride from Panama City Tocumen International Airport about three weeks in advance of your flight from MAO to Panama City.

Panama Pacifico International Airport (BLB)

  • The centre of Panama City is about 6 kilometres from Panama Pacifico International Airport (BLB). Once your flight from Manaus Eduardo Gomes International Airport to Panama City has landed and you've navigated your way to arrivals, the drive should be around 10 minutes.

  • If you choose to travel on public transport, the journey will take you 20 minutes or so.

  • After stepping off your MAO to Panama City flight, unwind at a hotel near BLB. These are some comfortable accommodation options that'll help you sink into relaxation mode:

  • Snap up the best price by securing your ride from BLB one week in advance. You can also expect to have a wider range of vehicles.

Best time to go to Panama City

  • It's time to plan your trip dates for your flight from Manaus Eduardo Gomes International Airport to Panama City. January is the most popular month to travel to Panama City. If you want a more peaceful vibe, go in September.

  • The warmest month in Panama City is March, with temperatures ranging between 21ºC (70ºF) and 32ºC (90ºF). Book your Manaus Eduardo Gomes International Airport to Panama City plane ticket then if you enjoy this type of weather.

  • January has average temperatures of between 22ºC (72ºF) and 31ºC (88ºF). Search for a cheap ticket from MAO to Panama City around that time if you'd rather travel in cooler conditions.

More about Panama City

  • Start your Panama City trip right by choosing the perfect place to stay. As soon as you've booked your flight from Manaus Eduardo Gomes International Airport to Panama City, check out our selection of hotels including:

  • There are so many things to do and see in this city it can be hard to know where to begin. Metropolitan Cathedral (Catedral Metropolitan), Casco Viejo and Independence Square are top sights which should feature on any good Panama City itinerary.

Explore more of Panama

  • Panama City has plenty going for it, but there are so many other parts of Panama waiting to be discovered. Around 322 kilometres west of Panama City, a trip to David will keep your itinerary packed. Start with leading attractions like Museo Antropológico y Etnográfico Dr. Roberto De La Guardia, Raptors To The Rescue and Unachi Botanical garden.

  • Next? Head off for Santiago de Veraguas. It's located about 193 kilometres southwest of Panama City and home to highlights like Santiago the Apostle Cathedral, Santiago de Veraguas.

Plan the rest of your trip from Manaus to Panama City

Prices shown on this page are estimated lowest prices only. Found in the last 12 days.